This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human CARD14
Swissprot
Q9BXL6
Synonyms
Bcl10 interacting MAGUK protein 2Bimp 2Bimp2CAR14CARD 14CARD containing MAGUK 2 proteinCARD containing MAGUK protein 2Card maguk protein 2CARD-containing MAGUK protein 2CARD14Carma 2Carma2Caspase recruitment domain containing protein 14Caspas
Calculated MW
113 kDa
Gene Accession
BC018142
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4