CAST Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Western Blot analysis of Lovo cell using CAST Polyclonal Antibody at dilution of 1:750
Western Blot analysis of Lovo cell using CAST Polyclonal Antibody at dilution of 1:750
Immunohistochemistry of paraffin-embedded Human gastic cancer using CAST Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human gastic cancer using CAST Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human colon cancer using CAST Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human colon cancer using CAST Polyclonal Antibody at dilution of 1:70
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

Circle
Product Name
CAST Polyclonal Antibody
Catalog Number
RD211022A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Immunogen Information

Circle
Immunogen
Recombinant protein of human CAST
Swissprot
P20810
Synonyms
BS 17Calpain inhibitorCalpastatinCastHeart type calpastatinICALMGC9402Sperm BS 17 componentSperm BS-17 component
Calculated MW
77 kDa
Gene Accession
BC013579

Applications

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Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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