Catenin beta Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70223A
Western Blot analysis of various samples using Catenin beta Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded Human colon tissue using Catenin beta Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Mosue kidney using Catenin beta Polyclonal Antibody at dilution of 1:500.
Immunofluorescence analysis of Mouse stomach using Catenin beta Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Human Colon using Catenin beta Polyclonal Antibody.
Product Name
Catenin beta Polyclonal Antibody
Catalog Number
RD70223A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse β-catenin
Swissprot
P35222,Q02248,Q9WU82
Synonyms
Beta cateninBeta-cateninCadherin associated proteinCatenin (cadherin associated protein)beta 188kDaCatenin beta 1Catenin beta-1CATNBCHBCATCTNB1CTNNBCTNNB1DKFZp686D02253FLJ25606FLJ37923OTTHUMP00000162082OTTHUMP00000165222OTTHUMP0000016522
Calculated MW
92 kDa
Observed MW
92 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:300-1:1000, IF 1:200-1:800
Concentration
0.97 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.