Caveolin-1 (CAV1),a multifunctional protein,is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor . Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma . However,other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers,especially in oral cancer . Recent study also show that CAV1 is involved in astric Cancer .
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Caveolin-1
Swissprot
Q03135,P49817,P41350
Synonyms
BSCL3CAVCAV1CAV1caveolae protein22 kDcaveolin 1 alpha isoformcaveolin 1 beta isoformCaveolin 1 caveolae protein 22kDaCaveolin-1Caveolin1cell growth-inhibiting protein 32CGL3LCCNSMSTP085OTTHUMP00000025031PPH3VIP 21VIP21
Calculated MW
20 kDa
Observed MW
20 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:500-1:1000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4