For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77839A
Western Blot analysis of Mouse liver and Human fetal lung tissue, hela cell and Mouse kidney tissue, Human brain malignant glioma tissue and K562 cell using CBR1 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human cervical cancer using CBR1 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human colon cancer using CBR1 Polyclonal Antibody at dilution of 1:40
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.