CBR1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75583A
Western Blot analysis of Mouse liver and Human fetal lung tissue, hela cell and Mouse kidney tissue, Human brain malignant glioma tissue using CBR1 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human breast cancer using CBR1 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human esophagus cancer using CBR1 Polyclonal Antibody at dilution of 1:40
Product Name
CBR1 Polyclonal Antibody
Catalog Number
RD75583A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
Immunogen Information
Immunogen
Recombinant protein of human CBR1
Swissprot
P16152
Synonyms
15 hydroxyprostaglandin dehydrogenase [NADP+]15-hydroxyprostaglandin dehydrogenase [NADP+]Carbonyl reductase [NADPH] 1Carbonyl Reductase 1CBR 1CBR1CBR1CRNNADPH dependent carbonyl reductase 1NADPH-dependent carbonyl reductase 1Prostaglandin 9 ket
Calculated MW
30 kDa
Gene Accession
BC002511
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas