CBS Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77783A
Western Blot analysis of Mouse pancreas and Human fetal liver tissue using CBS Polyclonal Antibody at dilution of 1:550
Product Name
CBS Polyclonal Antibody
Catalog Number
RD77783A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human CBS
Swissprot
P35520
Synonyms
AI047524AI303044Beta thionaseBeta-thionaseCbsCbs cystathionine beta-synthaseCBSCystathionine beta synthaseCystathionine beta-synthaseEC 4.2.1.22HIP 4HIP4Methylcysteine synthaseMGC18856MGC18895MGC37300OTTHUMP00000109416OTTHUMP00000109418S
Calculated MW
61 kDa
Gene Accession
BC010242
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas