CBX3 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85682A
Western Blot analysis of 1) Hela, 2) 3T3, 3) PC12 cells using CBX3 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human colon carcinoma tissue using CBX3 Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human placenta tissue using CBX3 Monoclonal Antibody at dilution of 1:200.
Product Name
CBX3 Monoclonal Antibody
Catalog Number
RD85682A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.
Immunogen Information
Immunogen
Recombinant Protein of HP-1γ
Swissprot
Q13185
Synonyms
CBX 3CBX3CBX3Chromobox homolog 3 (HP1 gamma homologDrosophila)Chromobox homolog 3Chromobox protein homolog 3GAMMAHECHHeterochromatin like protein 1Heterochromatin protein 1 homolog gammaHeterochromatin protein HP1 gammaHP1 gammaHP1 gamma homo
Observed MW
24 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:50-300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas