CBX3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76317A
Western Blot analysis of A375 and Raji cell, Human fetal brain tissue using CBX3 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human gastic cancer using CBX3 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human brain using CBX3 Polyclonal Antibody at dilution of 1:40
Product Name
CBX3 Polyclonal Antibody
Catalog Number
RD76317A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.
Immunogen Information
Immunogen
Synthetic peptide of human CBX3
Swissprot
Q13185
Synonyms
CBX 3CBX3CBX3Chromobox homolog 3 (HP1 gamma homologDrosophila)Chromobox homolog 3Chromobox protein homolog 3GAMMAHECHHeterochromatin like protein 1Heterochromatin protein 1 homolog gammaHeterochromatin protein HP1 gammaHP1 gammaHP1 gamma homo
Calculated MW
21 kDa
Gene Accession
NP_009207
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas