CCDC99 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75363A
Western Blot analysis of Hela cell, Mouse testis tissue and Jurkat cell using CCDC99 Polyclonal Antibody at dilution of 1:400
Product Name
CCDC99 Polyclonal Antibody
Catalog Number
RD75363A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
Immunogen Information
Immunogen
Recombinant protein of human SPDL1
Swissprot
Q96EA4
Synonyms
AA409762Arsenite related gene 1 proteinArsenite-related gene 1 proteinCCDC 99Ccdc99Coiled coil domain containing 99Coiled-coil domain-containing protein 99FLJ20364FLJ40690hSpindlyMGC124977Protein Spindlyrhabdomyosarcoma antigen MU RMS 40.4ARh
Calculated MW
70/59 kDa
Gene Accession
BC012568
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas