This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.
Immunogen Information
Immunogen
Synthetic peptide of human CCL1
Swissprot
P22362
Synonyms
C-C motif chemokine 1Ccl1CCL1Chemokine CC Motif Ligand 1inflammatory cytokine I-309P500SCYA1SISesmall inducible cytokine A1Small-inducible cytokine A1T lymphocyte secreted protein I-309T lymphocyte secreted protein I-309T lymphocyte-secreted p
Gene Accession
NP_002972
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4