This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis.
Immunogen Information
Immunogen
Fusion protein of human CCL13
Swissprot
Q99616
Synonyms
C-C motif chemokine 13CCL13CCL13Chemokine (C C motif) ligand 13CK beta 10CK-beta-10CKb10MCP-4MGC17134Monocyte chemoattractant protein 4Monocyte chemotactic protein 4NCC 1NCC-1NCC1New CC chemokine 1SCYA13SCYL1short chainSmall inducible cy