CCL2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76203A
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using CCL2 Polyclonal Antibody at dilution 1:50
Product Name
CCL2 Polyclonal Antibody
Catalog Number
RD76203A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Immunogen Information
Immunogen
Synthetic peptide of human CCL2
Swissprot
P13500
Synonyms
C-C motif chemokine 2CCL2CCL2Chemokine (C C motif) ligand 2GDCF 2GDCF-2GDCF2HC11HSMCR30JEMCAFMCP 1MCP-1MCP1MGC9434Monocyte chemoattractant protein 1Monocyte chemotactic and activating factorMonocyte chemotactic protein 1Monocyte secretor
Gene Accession
NP_002973
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:50
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas