This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
Immunogen Information
Immunogen
Synthetic peptide of human CCL23
Swissprot
P55773
Synonyms
C C motif chemokine ligand 23C-C motif chemokine 23C6 beta chemokineCCL 23CCL23CCL23(30-99)CCL23Chemokine (C C motif) ligand 23Chemokine CC motif ligand 23ck beta 8CK-beta-8CKB 8CKB-8Ckb-8-1CKB8Hmrp-2aMacrophage inflammatory protein 3MIP
Gene Accession
NP_005055
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4