The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse CCR7
Swissprot
P32248,P47774
Synonyms
BLR 2BLR2C C chemokine receptor type 7C C CKR 7C-C chemokine receptor type 7C-C CKR-7CC chemokine receptor 7CC chemokine receptor type 7CC CKR 7CC-CKR-7CCCKR7CCR 7CCR-7Ccr7CCR7CD 197CD197CD197 antigenCDw197Chemokine (C C motif) receptor
Calculated MW
43 kDa
Observed MW
48 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4