CD11B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Immunofluorescence analysis of Rat bone marrow using CD11B Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of RAW264.7 cells using CD11B Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of THP-1 cells using CD11B Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
CD11B Polyclonal Antibody
Catalog Number
RD82215A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human CD11B (NP_001139280.1).
Gene ID
3684
Swissprot
P11215
Synonyms
CD11BCR3AMAC-1MAC1AMO1ASLEB6ITGAMCD11b/ITAM
Applications