CD146/MCAM Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89409A
Western blot analysis of extracts of various cell lines using CD146/MCAM Polyclonal Antibody at 1:1000 dilution.
Product Name
CD146/MCAM Polyclonal Antibody
Catalog Number
RD89409A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Immunogen Information
Immunogen
Recombinant fusion protein of human CD146/MCAM
Gene ID
4162
Swissprot
P43121
Synonyms
MCAMCD146MUC18cell surface glycoprotein MUC18
Calculated MW
58kDa/73kDa/84kDa
Observed MW
Refer to figures
Applications
Reactivity
Human,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas