Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.
Immunogen Information
Immunogen
Recombinant protein of human KLRC1
Swissprot
P26715
Synonyms
C lectin type II proteinCD159 antigen like family member ACD159 antigen-like family member ACD159aCD159a antigenKiller cell lectin like receptor subfamily C member 1KLRC1MGC13374MGC59791Natural killer cell lectinNatural killer cell protein group
Gene Accession
BC053840
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4