CD16 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85507A
Western Blot analysis of 1) Jurkat, 2) K562 cells using CD16 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human liver tissue using CD16 Monoclonal Antibody at dilution of 1:200.
Product Name
CD16 Monoclonal Antibody
Catalog Number
RD85507A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P08637,O75015
Synonyms
CD 16CD 16aCD16CD16aCD16BFc fragment of IgGFc fragment of IgG low affinity IIIa receptor (CD16)Fc gamma R3Fc gamma receptor III 2 (CD 16)Fc gamma receptor III AFc of IgGFc-gamma receptor III2 (CD 16)Fc-gamma RIIIFc-gamma RIII-alphaFc-gamma R
Calculated MW
28 kDa
Observed MW
45 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-p
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas