CD177 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD83893A
Western blot analysis of extracts of BT-474 cells using CD177 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of BT-474 cells using CD177 Polyclonal Antibody at dilution of 1:1000.
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Overview

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Product Name
CD177 Polyclonal Antibody
Catalog Number
RD83893A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Immunogen Information

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Immunogen
Recombinant fusion protein of human CD177 (NP_065139.2).
Gene ID
57126
Swissprot
Q8N6Q3
Synonyms
CD177HNA-2aHNA2ANB1NB1 GPPRV-1PRV1NB1GP
Calculated MW
15 kDa/27 kDa/46 kDa
Observed MW
45 kDa

Applications

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Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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