This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse CCR2
Swissprot
P41597,P51683,O55193
Synonyms
C C chemokine receptor type 2C C CKR 2C-C chemokine receptor type 2C-C CKR-2CC chemokine receptor type 2CC CKR 2CC-CKR-2CCCKR2CCR 2CCR-2CCR1LCCR2CCR2CCR2ACCR2BCCR5LCD192CD192 antigenChemokine C C motif receptor 2Chemokine CC Motif Recep
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:300-1:1000
Concentration
1.35 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4