The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene.CD2 (CD2 Molecule) is a Protein Coding gene. Diseases associated with CD2 include Penis Squamous Cell Carcinoma and Immune Defect Due To Absence Of Thymus. Among its related pathways are PEDF Induced Signaling and TGF-Beta Pathway. GO annotations related to this gene include protein homodimerization activity and receptor activity.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P06729
Synonyms
CD 2CD2CD2 antigen (p50)sheep red blood cell receptorCD2 antigenCD2 moleculeCD2Erythrocyte receptorFLJ46032LFA-2LFA-3 receptorLFA2LFA3 receptorLy-37Lymphocyte function antigen 2lymphocyte-function antigen-2OTTHUMP00000024366Rosette recept
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC-p
Conjugation
Unconjugated
Dilution
IHC 1:50-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.