CD20 is a 33-37 kDa transmembrane phosphoprotein. CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny,from early pre-B-cell developmental stages until final differentiation into plasma cells. CD20 functions as calcium-permeable cation channel. It is involved in the regulation of B-cell activation and proliferation. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B-cells.
Immunogen Information
Immunogen
Recombinant Mouse CD20 protein expressed by E.coli
Swissprot
P19437
Synonyms
APYATOPYB lymphocyte antigen CD20B Lymphocyte Cell Surface Antigen B1Bp35CD20CD20 antigenCD20 receptorCVID5Fc epsilon receptor I beta chainIGELIGERIGHERLEU16leukocyte surface antigen Leu 16MS4A1S7
Calculated MW
25kDa
Observed MW
25kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.