CD22 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77934A
Immunohistochemistry of paraffin-embedded Human brain tissue using CD22 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CD22 Polyclonal Antibody at dilution 1:50
Product Name
CD22 Polyclonal Antibody
Catalog Number
RD77934A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The B lymphocyte specific CD22 antigen, also designated B-lymphocyte cell adhesion molecule (BLCAM), sialic acid-binding Ig-like lectin 2 (Siglec-2) and Leu-14, is a type I integral membrane glycoprotein, structurally similar to other cell adhesion molecules (CAMs), which acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells.
Immunogen Information
Immunogen
Recombinant protein of human CD22
Swissprot
P20273
Synonyms
B cell receptor CD22 precursorB lymphocyte cell adhesion moleculeB-cell receptor CD22B-lymphocyte cell adhesion moleculeBL CAMBL-CAMBLCAMCD 22CD22CD22 antigenCD22 moleculeCD22 proteinCD22Lectin 2Leu14Lyb8MGC130020sialic acid binding Ig li
Gene Accession
BC109306
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas