Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human GYPC
Swissprot
P04921
Synonyms
CD236CD236RGEGLPCGLPCGlycoconnectinGlycophorin C (Gerbich blood group)Glycophorin DGlycophorin-CGlycophorin-DGlycoprotein betaGPCGPDGypcGYPDMGC117309MGC126191MGC126192PAS 2PAS 2'PAS-2''Sialoglycoprotein D
Gene Accession
BC104246
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4