CD27 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of Raji, PC3 and lovo cell using CD27 Polyclonal Antibody at dilution of 1:727
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CD27 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human brain using CD27 Polyclonal Antibody at dilution of 1:60
Product Name
CD27 Polyclonal Antibody
Catalog Number
RD77937A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Immunogen Information
Immunogen
Recombinant protein of human CD27
Swissprot
P26842
Synonyms
CD 27CD27CD27 antigenCD27 moleculeCD27CD27L receptorLPFS2MGC20393OTTHUMP00000238557S152T cell activation antigen CD27T cell antivation antigen S152T-cell activation antigen CD27T14TNFRSF 7TNFRSF7TNFSF7Tp 55Tp55Tumor necrosis factor rece
Calculated MW
29 kDa
Gene Accession
BC012160
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas