CD284 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70430A
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD284 Monoclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded rat spleen using CD284 Monoclonal Antibody at dilution of 1:400.
Product Name
CD284 Monoclonal Antibody
Catalog Number
RD70430A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Mouse
Background
TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse TLR4
Swissprot
Q9QUK6,Q9QX05
Synonyms
ARMD10CD284CD284 antigenHomolog of Drosophila tollhTollTLR 4TLR4TLR4TOLLToll like receptor 4Toll-like receptor 4
Applications
Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:800
Concentration
1.8 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas