CD2AP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78946A
Western Blot analysis of A431 and Raji cell using CD2AP Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human Lymphoma using CD2AP Polyclonal Antibody at dilution of 1:70
Immunohistochemistry of paraffin-embedded Human liver cancer using CD2AP Polyclonal Antibody at dilution of 1:70
Product Name
CD2AP Polyclonal Antibody
Catalog Number
RD78946A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Immunogen Information
Immunogen
Synthetic peptide of human CD2AP
Swissprot
Q9Y5K6
Synonyms
Adapter protein CMSAL024079C78928Cas ligand with multiple SH3 domainsCD2 associated proteinCD2-associated proteinCD2APCD2APCMSMesenchyme to epithelium transition protein with SH3 domains 1METS 1Mets1
Calculated MW
71 kDa
Gene Accession
NP_036252
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:100-1:300
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas