CD40 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78955A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD40 Polyclonal Antibody at dilution 1:70
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CD40 Polyclonal Antibody at dilution 1:70
Product Name
CD40 Polyclonal Antibody
Catalog Number
RD78955A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, whicHuman, Mouseay be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
Immunogen Information
Immunogen
Synthetic peptide of human CD40
Swissprot
P25942
Synonyms
AI326936B cell associated molecule CD40B cell surface antigen CD40B cell-associated moleculeB-cell surface antigen CD40Bp50CD 40CD40CD40 antigen (TNF receptor superfamily member 5)CD40 antigenCD40 moleculeCD40 moleculeTNF receptor superfamily
Gene Accession
NP_001241
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
1.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas