CD45 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85467A
Western Blot analysis of Hela cells using CD45 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human liver cancer tissue using CD45 Monoclonal Antibody at dilution of 1:200.
Product Name
CD45 Monoclonal Antibody
Catalog Number
RD85467A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P08575
Synonyms
B220CD 45CD45CD45 antigenCD45RGP180L-CALCALeukocyte common antigenlocLy-5LY5Ly5homolog ofLyt-4OTTHUMP00000033813OTTHUMP00000033816OTTHUMP00000033817OTTHUMP00000038574Protein tyrosine phosphatase receptor type c polypeptideProtein tyros
Calculated MW
147 kDa
Observed MW
147 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-p
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.