CD54 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78959A
Western Blot analysis of Huvec, hela and raji cell using CD54 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human lung cancer using CD54 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human breast cancer using CD54 Polyclonal Antibody at dilution of 1:40
Product Name
CD54 Polyclonal Antibody
Catalog Number
RD78959A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Immunogen Information
Immunogen
Synthetic peptide of human ICAM1
Swissprot
P05362
Synonyms
Antigen identified by monoclonal BB2BB 2BB2CD 54CD_antigen=CD54CD54Cell surface glycoprotein P3.58Human rhinovirus receptorICAM 1ICAM-1ICAM1ICAM1intercellular adhesion molecule 1 (CD54)human rhinovirus receptorIntercellular adhesion molecule
Calculated MW
58 kDa
Gene Accession
NP_000192
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas