CD5L (CD5 molecule-like), also known as API6, PRO229, Spalpha or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.
Immunogen Information
Immunogen
Synthetic peptide of human CD5L
Swissprot
O43866
Synonyms
AAC-11AIMAPI6APOPTOSIS INHIBITOR 6APOPTOSIS INHIBITOR OF MACROPHAGESCD5 antigen like (scavenger receptor cysteine rich family)CD5 antigen-likeCd5lCD5LCT 2CT-2Highly similar to ANTIGEN WC1.1 [Bos taurus]IgM associated peptideIgM-associated pep
Gene Accession
NP_005885
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4