CD74 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD6298
Immunohistochemistry of paraffinembedded Human tonsil tissue with CD74 Monoclonal Antibody(Antigen repaired by EDTA). Location: Cell membrane.
Product Name
CD74 Monoclonal Antibody
Catalog Number
RD6298
Clonality
Monoclonal
Host
Mouse
Background
CD74 is a membrane binding subunit of the class II related invariant chain of the major histocompatibility complex. CD74 is mainly used to label lymphocytes in germinal center and in the mantle cell area of lymph nodes. This antibody does not label plasma cells or thymocytes, but usually labels dendritic cells. About 90% of low-grade B-cell lymphoma and 20% of low-grade T-cell lymphoma are expressing CD74, but in high-grade lymphoma, the ability to distinguish B cells from T cells is decreased.
Immunogen Information
Swissprot
P04233
Applications
Reactivity
Human
Tested Applications
Ready to use for IHC-P
Concentration
100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Storage Buffer
TBS with 0.1% Proclin300, PH7.4