CD74 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90727A
Immunohistochemistry of paraffin-embedded Human tonsil using CD74 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human lung using CD74 Polyclonal Antibody at dilution of 1:400
Product Name
CD74 Polyclonal Antibody
Catalog Number
RD90727A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen Information
Immunogen
Recombinant Mouse Cd74 protein expressed by E.coli
Swissprot
P04441
Synonyms
CD 74CD74CD74 antigen (invariant polypeptide of major histocompatibility complexclass II antigen-associated)CD74 antigenCD74 moleculeCD74 moleculemajor histocompatibility complexclass II invariant chainCLIPDHLAGGamma chain of class II antigens
Applications
Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:400
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas