This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response.
Immunogen Information
Immunogen
Recombinant protein of human LILRB2
Swissprot
Q8N423
Synonyms
CD85 antigen-like family member DCD85dCD85d antigenILT 4ILT-4ILT4Immunoglobulin like transcript 4Immunoglobulin-like transcript 4Leukocyte immunoglobulin like receptor 2Leukocyte immunoglobulin like receptor subfamily B member 2Leukocyte immunog
Gene Accession
BC036827
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4