CDC25A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78694A
Western Blot analysis of 231 and A549 cell using CDC25A Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human gastic cancer using CDC25A Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CDC25A Polyclonal Antibody at dilution of 1:50
Product Name
CDC25A Polyclonal Antibody
Catalog Number
RD78694A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human CDC25A
Swissprot
P30304
Synonyms
Cdc 25aCDC25ACDC25A2CDC25A2 CAG isoformCell division cycle 25 homolog A (S. pombe)Cell division cycle 25ACell division cycle 25A isoform aCell division cycle 25A isoform bD9Ertd393eDual specificity phosphatase Cdc25AM phase inducer phosphatase 1
Calculated MW
59 kDa
Gene Accession
NP_001780
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas