CDC25B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76495A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDC25B Polyclonal Antibody at dilution 1:45
Immunohistochemistry of paraffin-embedded Human brain tissue using CDC25B Polyclonal Antibody at dilution 1:45
Variation
Quantity
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Overview
Product Name
CDC25B Polyclonal Antibody
Catalog Number
RD76495A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Immunogen Information
Immunogen
Synthetic peptide of human CDC25B
Swissprot
P30305
Synonyms
AI604853Cdc 25BCdc25bCDC25HU2Cdc25m2Cell division cycle 25 homolog BCell division cycle 25BCell division cycle 25B isoform 1Cell division cycle 25B isoform 2Cell division cycle 25B isoform 3Cell division cycle 25B isoform 4Cell division cycle 2
Gene Accession
NP_004349
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas