CDK1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70486A
Western Blot analysis of various samples using CDK1 Polyclonal Antibody at dilution of 1:1000.
Product Name
CDK1 Polyclonal Antibody
Catalog Number
RD70486A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. CDC2 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. It is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. Mitotic cyclins stably associate with CDC2 and function as regulatory subunits. The antibody is specific to the 2 isoforms of CDC2.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to mouse CDK1
Swissprot
P06493,P11440,P39951
Synonyms
Cdc 2Cdc2CDC28ACDK 1CDK1CDK1CDKN1CELL CYCLE CONTROLLER CDC2Cell division control protein 2Cell division control protein 2 homologCell division cycle 2 G1 to S and G2 to MCell division protein kinase 1Cell Divsion Cycle 2 ProteinCyclin Depende
Calculated MW
34 kDa
Observed MW
34 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
2.5 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.