The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.
Immunogen Information
Immunogen
Synthetic peptide of human CDT1
Swissprot
Q9H211
Synonyms
CDT 1cdt1CDT1Chromatin licensing and DNA replication factor 1DNA replication factorDNA replication factor Cdt1Double parkedDouble parked Drosophila homolog ofDouble parked homologDUPRetroviral integration site 1Retroviral integration site 2Ret