CEBPA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80152A
Western blot analysis of extracts of Mouse lung using CEBPA Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Rat liver using CEBPA Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat brain using CEBPA Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat kidney using CEBPA Polyclonal Antibody at dilution of 1:100 (40x lens).
Product Name
CEBPA Polyclonal Antibody
Catalog Number
RD80152A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.
Immunogen Information
Immunogen
Recombinant fusion protein of human CEBPA (NP_004355.2).
Gene ID
1050
Swissprot
P49715
Synonyms
CEBPAC/EBP-alphaCEBP
Calculated MW
25 kDa/35 kDa/37 kDa/41 kDa
Observed MW
41 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.