CELA3B Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD87701A
Western blot analysis of extracts of rat pancreas using CELA3B Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of rat pancreas using CELA3B Polyclonal Antibody at 1:3000 dilution.
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Overview

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Product Name
CELA3B Polyclonal Antibody
Catalog Number
RD87701A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.

Immunogen Information

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Immunogen
Recombinant fusion protein of human CELA3B
Gene ID
23436
Swissprot
P08861
Synonyms
CELA3BCBPPELA3B
Calculated MW
29kDa
Observed MW
29kDa

Applications

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Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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