CENPC Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75700A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using CENPC Polyclonal Antibody at dilution 1:70
Variation
Quantity
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Overview
Product Name
CENPC Polyclonal Antibody
Catalog Number
RD75700A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Immunogen Information
Immunogen
Recombinant protein of human CENPC
Swissprot
Q03188
Synonyms
CENP-C 1CENP-CCENPCCENPC1Centromere autoantigen CCentromere autoantigen C1Centromere protein C 1Centromere protein Chcp-4ICEN7Interphase centromere complex protein 7MIF2
Gene Accession
BC030695
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas