CENPE Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD88135A
Western blot analysis of extracts of various cell lines using CENPE Polyclonal Antibody at1:1000 dilution.
Western blot analysis of extracts of various cell lines using CENPE Polyclonal Antibody at1:1000 dilution.
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Overview

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Product Name
CENPE Polyclonal Antibody
Catalog Number
RD88135A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.

Immunogen Information

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Immunogen
Recombinant fusion protein of human CENPE
Gene ID
1062
Swissprot
Q02224
Synonyms
CENPECENP-EKIF10MCPH13PPP1R61
Calculated MW
16kDa
Observed MW
14kDa

Applications

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Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:200-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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