CERK Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77845A
Immunohistochemistry of paraffin-embedded Human tonsil tissue using CERK Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CERK Polyclonal Antibody at dilution 1:50
Product Name
CERK Polyclonal Antibody
Catalog Number
RD77845A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
Immunogen Information
Immunogen
Recombinant protein of human CERK
Swissprot
Q8TCT0
Synonyms
Acylsphingosine kinaseCeramide kinaseCerkCERK1dA59H18.2dA59H18.3hCERKKIAA1646Lipid kinase 4Lipid kinase LK4LK4
Gene Accession
BC126940
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas