This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD).
Immunogen Information
Immunogen
Synthetic peptide of human CERKL
Swissprot
Q49MI3
Synonyms
Ceramide kinase like proteinCeramide kinase-like proteinCERKLCERKLRetinitis pigmentosa 26 (autosomal recessive)RP26
Calculated MW
63 kDa
Gene Accession
NP_001025482
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4