CERS6 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79123A
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CERS6 Polyclonal Antibody at dilution 1:35
Immunohistochemistry of paraffin-embedded Human brain tissue using CERS6 Polyclonal Antibody at dilution 1:35
Product Name
CERS6 Polyclonal Antibody
Catalog Number
RD79123A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.
Immunogen Information
Immunogen
Synthetic peptide of human CERS6
Swissprot
Q6ZMG9
Synonyms
Ceramide synthase 6CerS 6CERS5CerS6LAG1 homolog ceramide synthase 6LAG1 longevity assurance homolog 6LASS 6Lass6LASS6Longevity assurance homolog 6MGC129949MGC129950T1L
Gene Accession
NP_982288
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas