CFL1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70065A
Western Blot analysis of A431 and Jurkat cells using CFL1 Polyclonal Antibody at dilution of 1:600
Product Name
CFL1 Polyclonal Antibody
Catalog Number
RD70065A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Immunogen Information
Immunogen
Recombinant human Homeobox protein Cofilin-1 protein
Swissprot
P23528
Synonyms
18 kDa phosphoproteinCFL 1CFLCFL1COF1Cofilin 1Cofilin 1 non muscleCofilinCofilin non muscle isoformCofilin-1epididymis secretory protein Li 15HEL-S-15non-muscle isoformp18
Calculated MW
17 kDa
Observed MW
17 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas