CHOP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Immunohistochemistry analysis of paraffin-embedded human colon using CHOP Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CHOP Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse brain using CHOP Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded Rat brain using CHOP Polyclonal Antibody at dilution of 1:300.
Product Name
CHOP Polyclonal Antibody
Catalog Number
RD70297A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CHOP,also known as GADD153 or DDIT3,is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins,CHOP is significantly induced by ER stress,deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse CHOP
Swissprot
P35638,P35639,Q62857
Synonyms
C/EBP homologous proteinC/EBP Homology ProteinC/EBP zetaC/EBP-homologous protein 10C/EBP-homologous proteinCCAAT/enhancer binding protein homologous proteinCEBPZCHOP 10CHOPCHOP-10CHOP10DDIT 3DDIT-3Ddit3DDIT3DNA Damage Inducible Transcript 3
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:100-500
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.