CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 or CASP families. Expression of CIAPIN1 is dependent on growth factor stimulation. Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein NDOR1.
Immunogen Information
Immunogen
Recombinant protein of human CIAPIN1
Swissprot
Q6FI81
Synonyms
2810413N20RikAnamorsinCIAPIN 1CIAPIN1CPIN1Cytokine induced apoptosis inhibitor 1Cytokine-induced apoptosis inhibitor 1DRE2Fe-S cluster assembly protein DRE2 homologPredicted protein of HQ0915PRO0915
Calculated MW
34 kDa
Gene Accession
BC024196
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4