This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21.
Immunogen Information
Immunogen
Synthetic peptide of human KRT10
Swissprot
P13645
Synonyms
BCIEBIECK 10CK-10Cytokeratin-10EHKK10K1C10Keratin 10Keratin 10 type IKeratinKeratin type i cytoskeletal 10Keratin type I cytoskeletal 59 kDaKeratin-10Keratin10KPPKRT10type I cytoskeletal 10
Calculated MW
59 kDa
Gene Accession
NP_000412
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4